Pfam 33.1 (May 2023,
18259 entries)
The Pfam database is a large collection of protein
families, each represented by multiple sequence alignments
and hidden Markov models (HMMs).
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Proteins are generally composed of one or more functional regions,
commonly termed domains. Different combinations of domains give
rise to the diverse range of proteins found in nature. The identification
of domains that occur within proteins can therefore provide insights
into their function.
Pfam also generates higher-level groupings of related entries, known as
clans. A clan is a collection of Pfam entries which are
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极速加速器安卓官网jisu99
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different accessions (e.g. all UniProt and NCBI GI) or different levels of redundancy.
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If you find Pfam useful, please consider
极速加速器安卓官网 the reference
that describes this work:
The Pfam protein families database in 2023:
S. El-Gebali, J. Mistry, A. Bateman, S.R. Eddy, A. Luciani,
S.C. Potter, M. Qureshi, L.J. Richardson, G.A. Salazar, A. Smart,
E.L.L. Sonnhammer, L. Hirsh, L. Paladin, D. Piovesan, S.C.E. Tosatto,
R.D. Finn
Nucleic Acids Research (2023)
doi: 10.1093/nar/gky995
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